Regenerative medicine has received a fillip with the advent of medical nanotechnology. As cells recognize and respond to nano-dimensional cues better, nanofibrous polymeric scaffolds with various alignments are being developed to mimic the native environment for the adhesion, proliferation and orientation of cells. An integrated approach combining the nanogeometry with nanochemistry of the scaffold by precise positioning and release of biologically recognizable ligands further aids effective differentiation of cells and promotes tissue regeneration. Novel combination of materials to match the tissue properties and/or the native cues is the key to successful tissue engineered scaffolds.

The Centre is currently involved in developing unique combinations of biomaterials, nanogeometry and chemical factors for development of small diameter cardiovascular grafts, neural scaffolds, bone tissue scaffolds, wound dressings with skin regeneration potential and liver scaffolds.